منابع مشابه
Capillary fluid exchange.
To understand the functional aspects of the microcirculation, the student must understand that the circulation in our bodies is a pressurized system (see Fig. 1A). When the blood leaves the heart to enter the aorta, it produces an average vascular pressure in the large arteries of ,100 mmHg. However, as the blood flows through the smallest arteries (arterioles), its pressure decreases to 30–40 ...
متن کاملModeling alveolar capillary dysplasia.
To the Editor, I read with great interest the article by Han et al,1 who studied lung morphology in developing endothelial NO synthase (eNOS)deficient mice. The authors presented exciting data on defective peripheral lung vessel development, which was combined with impaired alveolar maturation. These data reflect very well the current thinking of lung development regulated by molecular cross-ta...
متن کاملArteriovenous pairing: a determinant of capillary exchange.
Venuloarteriolar signaling helps mediate microvascular function and dysfunction. Mediators produced at venular sites of inflammation appear to constrict arterioles and increase capillary permeability. In contrast, venules beneficially dilate arterioles to enhance capillary flow according to metabolic demand. These mechanisms are altered with cardiovascular risk factors, contributing to microvas...
متن کاملTranscapillary Exchange in Relation to Capillary Circulation
Transcapillary exchange of diffusible solutes depends on capillary blood flow, Q; capillary permeability, P; and capillary surface area, S. In a single capillary, the extent of equilibration of a given solute depends on the ratio of Q, to the product of P and S. In a microvascular bed consisting of many capillaries, equilibration depends on the fraction of them which are open to blood flow at a...
متن کاملA model of nitric oxide capillary exchange.
OBJECTIVE Our aim was to develop a mathematical model that describes the nitric oxide (NO) transport in and around capillaries. The model is used to make quantitative predictions for (1) the contribution of capillary endothelium to the nitric oxide flux into the parenchymal tissue cells; (2) the scavenging of arteriolar endothelium-derived NO by capillaries in the surrounding tissue; and (3) th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 1970
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.27.5.739